Hotest Blockchain News in First Media Index

Mice exhibit self-recognition-like behavior in mirror test, says study

Mice have recently joined a select group of animals that have passed the mirror self-recognition test (MSR) — a commonly recognized indicator of self-awareness. 

This exclusive club also includes great apes, bottlenose dolphins, and European magpies, to name a few. 

Recently, a team of researchers performed a set of experiments in which they marked the foreheads of black-furred mice with white and black ink marks. 

Upon observing their reflections in the mirror, the mice attempted to remove the ink stain from their foreheads.

A statement by the researchers highlighted that “the mice only showed this self-recognition-like behavior if they were already accustomed to mirrors if they had socialized with other mice who looked like them, and if the ink spot was relatively large.”

  • Scientists engineer first mice to tolerate COVID-19 like young humans 
  • Targeted nerve regeneration improves walking in mice 
  • MIT researchers surprised mice to learn how humans judge risky behavior 

Grooming behavior changed in size and color

However, the authors emphasized that the mice’s ability to perceive changes in their appearance does not inherently imply self-awareness. 

While mice with white ink spent a lot of time trying to remove the spot from their heads, they didn't think about grooming other parts of their bodies in front of the mirror.

On the other hand, mice with black spots similar to their fur did not at all groom their heads. This behavioral pattern was consistent when the black and white ink spots were small in size. 

The observed behaviors suggested a nuanced response to changes in appearance, highlighting that grooming reactions may be influenced by factors such as spot color and size rather than solely indicating self-awareness.

“The mice required significant external sensory cues to pass the mirror test—we have to put a lot of ink on their heads, and then the tactile stimulus coming from the ink somehow enables the animal to detect the ink on their heads via a mirror reflection. Chimps and humans don't need any of that extra sensory stimulus,” stated Jun Yokose of the University of Texas Southwestern Medical Center, and the first author.

Gene expression mapping

Through gene expression mapping, the researchers pinpointed a specific group of neurons in the ventral hippocampus that became active when the mice seemingly "recognized" themselves in the mirror. 

The researchers deliberately disrupted the function of these neurons to investigate the relationship between them and the observed grooming behavior. 

As a result, the mice were no longer groomed in response to the mirror and the presence of ink markings.

Furthermore, the researchers discovered that a portion of these neurons responded not just when the mice looked in the mirror, but also when they watched other mice of the same strain. 

In response to mice with identical physical features and fur colors, these neurons were stimulated. 

This shows that these neurons are involved in identifying self and others based on physical likeness, which influences grooming behavior observed in the presence of mirrors and ink markings.

According to the authors, this gene mapping gives the first sight into the cerebral processes behind self-recognition, "something that was previously a black box in neurobehavioral research."

“To form episodic memory, for example, of events in our daily life, brains form and store information about where, what, when, and who, and the most important component is self-information or status. Researchers usually examine how the brain encodes or recognizes others, but the self-information aspect is unclear,” said Takashi Kitamura, neuroscientist and senior author.

The findings were reported earlier today [December 5] in the journal Neuron.

Add Interesting Engineering to your Google News feed.
Add Interesting Engineering to your Google News feed.

Hotest Cryptocurrency News

End of content

No more pages to load

Next page